AICAR (Acadesine)

AICAR – Available in 50mg and 100mg vial

Metabolic Research Compound for AMPK Activation & Cellular Energy Regulation

AICAR (5-Aminoimidazole-4-carboxamide ribonucleotide), also known as Acadesine, is a research compound widely studied in metabolic science due to its interaction with AMP-activated protein kinase (AMPK), a key regulator of cellular energy balance and metabolic activity.

AICAR has attracted scientific interest for its role in laboratory models investigating glucose metabolism, fatty acid oxidation, mitochondrial function and cellular energy regulation. Researchers use this compound to explore the biological mechanisms involved in energy utilisation, metabolic adaptation and nutrient signalling.

Key Features

✓ Studied for its interaction with AMPK-related metabolic pathways
✓ Frequently researched in cellular energy regulation models
✓ Investigated for its effects on glucose metabolism
✓ Used in laboratory studies examining fatty acid oxidation
✓ Explored in mitochondrial function and energy metabolism research
✓ Popular within metabolic health, exercise physiology and cellular energy research

AMPK Activation Research

AICAR is commonly investigated for its ability to activate AMPK-related signalling pathways. AMPK acts as a cellular energy sensor, helping regulate metabolic processes in response to changes in energy availability.

Fatty Acid Oxidation Research

Researchers study AICAR in laboratory models examining fatty acid oxidation and the mechanisms involved in cellular energy utilisation.

Glucose Metabolism Research

AICAR is investigated for its influence on glucose uptake and glucose metabolism, providing insight into the cellular pathways involved in energy balance.

Mitochondrial Function Studies

Research explores the relationship between AICAR, mitochondrial activity and cellular energy production, particularly in models examining metabolic adaptation.

Scientific Research Context

AMP-activated protein kinase (AMPK) plays an important role in maintaining cellular energy homeostasis. It acts as a metabolic regulator, responding to changes in the AMP-to-ATP ratio and influencing processes involved in energy production and consumption.

AICAR is a cell-permeable precursor of ZMP, an AMP mimetic that can influence AMPK signalling. This makes it a valuable research tool for investigating:

• AMPK activation and metabolic signalling
• Glucose uptake and utilisation
• Fatty acid oxidation
• Mitochondrial energy metabolism
• Cellular energy homeostasis
• Metabolic adaptation and nutrient signalling
• Exercise physiology and metabolic research

These research areas continue to drive scientific interest in AICAR and its interaction with cellular energy pathways.

Common Research Applications

AICAR is frequently studied in laboratory models involving:

• AMPK activation and signalling pathways
• Glucose metabolism and cellular uptake
• Fatty acid oxidation mechanisms
• Mitochondrial function and energy production
• Cellular energy regulation
• Metabolic adaptation research
• Exercise physiology studies
• Nutrient utilisation and energy balance

Related Research Compounds

Researchers investigating metabolic pathways and cellular energy regulation may also study:

5-Amino-1MQ – NNMT inhibition and metabolic regulation research.

MOTS-C – mitochondrial signalling and metabolic adaptation research.

AOD-9604 – fat metabolism and adipose tissue research.

These compounds are explored in different areas of metabolic science and cellular energy regulation.

Product Specifications

Product Name: AICAR (Acadesine)
Compound Type: Small-Molecule Research Compound
Research Category: Metabolic & Cellular Energy Research
Primary Target: AMPK-Related Signalling Pathways
Physical Form: Research Grade Powder
Available Sizes: 50mg, 100mg and 500mg Vials
Application: Scientific Research Use Only

Important Notice

For laboratory research use only. This product is intended solely for research, analytical and educational purposes. It is not intended for human or animal consumption, therapeutic use, veterinary use, diagnostic procedures or administration of any kind.